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Perindopril |
| Chemical Name: |
1-[2-(1-Ethoxycarbonylbutylamino)propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid 2-methyl-2-propanamine |
| Structural Formula: |
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| Molecular Formula: |
C19H32N2O5·C4H11N |
| Brief Intro.: |
As ACE inhibitor used in the treatment of hypertension and heat failure etc. |
ITEMS
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REQUIREMENT
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TEST METHODS
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Appearance
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White crystalline powder
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Eyeballing |
Identification |
IR |
CP2005 Version second part AddendumⅣ C |
Purity |
≥98.5% |
HPLC |
Specific optical rotation |
-66°to -69° |
CP2005 Version second part Addendum ⅥE |
Metling point |
156～158℃ |
Version second part Addendum VI C |
Residue on ignition |
≤0.1% |
CP2005 Version second part AddendumⅧ N |
Assay |
98.5～101.0%(Anhydrous substance)
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CP2005 Version second part Addendum Ⅶ B |
Total impuritles |
≤1.0% |
HPLC |
Heavy metal |
≤20PPM |
CP2005 Version second part AddendumⅧ H |
Water |
≤1.0 % |
K．F |
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| Packing: |
5kgs, 25kgs cardboard drum lined with double-layer plastic bag |
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